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In clinical trials, the most common observations were gastrointestinal effects: nausea (44.2% vs 17.4% placebo in STEP 1), diarrhea (30.0%), vomiting (24.8%), and constipation (24.2%)
The strong clinical backing provides assurance and reliability
It is advisable to maintain at least 2.55 centimetres distance between consecutive injection sites, even when using the same general body area
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The flagship trial STEP-1 (published in NEJM , 2021) found a mean weight reduction of ~14.9% of body weight with semaglutide 2.4 mg vs ~2.4% with placebo over 68 weeks ( [12] )
Works for various skin types and aims at different goals, from glow-ups to anti-aging
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