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Notably, we found that C6648: Meis2.GABA-5 neurons are the most affected by GLP-1R agonism, and C6645: Ghrh.GABA-3 neurons are most affected by GIPR agonism, but both of these populations were less affected after treatment with the GIPR:GLP-1R co-agonist MAR709 (Extended Data Fig

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Fluorescence microscopy Epifluorescence microscopy NAPstar or HyPer7 expressing HeLa cells were analysed with a Zeiss Axio Observer 7 inverted epifluorescence microscope and the ZEN3.2 blue edition software (Carl Zeiss AG, Oberkochen, Germany)