In the context of tirzepatide therapy, which strongly improves insulin sensitivity, this is unlikely to be a problem, but it is worth monitoring in individuals with diabetes or prediabetes
Curr Pharm Des 19:25122528
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Acute treatment of diet-induced obese mice with labelled semaglutide has been shown to allow the drug to access circumventricular organs that lack a substantial blood brain barrier, including the area postrema (AP), median eminence (ME), vascular organ of the lamina terminalis (OV), and subfornical organ (SFO) ( Figure 3 )
when the basics are solid but the metabolic math still feels off, Levocarnitine offers another lever to test
A real-world cohort study looked at the risks of developing ICIP in NSCLC patients who received prior radiotherapy and are currently on ICI therapy