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Global epidemiology of anabolicandrogenic steroid use

By restoring this missing hormonal feedback, you regain normal hunger cues, reduce cravings, and achieve calorie deficit without the constant psychological strain of fighting your own metabolism

Variants that reduce CYP activity can slow initial metabolism, but if phase II is also impaired, reactive metabolites can still accumulate and damage DNA, mitochondria, and tissues like the liver and kidneys

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Reston, VA, American College of Radiology

Reviews in Endocrine & Metabolic Disorders, 15 (3), 181187