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Propensity score matching was used to balance the baseline demographic, clinical, and RMS characteristics, as well as use of prior DMT between cohorts

10.1124/jpet.102.041616 227 ThomasL.FlorioT.Perez-CastroC

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It mainly includes scavenging free radicals (NOS) to alleviate the damage of melanocytes caused by oxidative stress, activating melanogenesis related pathways, increasing the expression of tyrosinase gene, reducing the expression of chemokines and inflammatory cytokines, preventing the migration of CD8 + T cells