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GLP-1s, with brand names like Ozempic and Wegovy, work by slowing the movement of food through the digestive tract keeping it in the stomach longer and also affecting the brains reward centers related to food

Molinari C, Uberti F, Grossini E, Vacca G, Carda S, Invernizzi M, Cisari C

doi: 10.1111/nmo.12669 214

Adding this anabolic support to a retatrutide-driven caloric deficit could theoretically shift the composition of weight loss toward greater fat loss and less muscle loss

This is when moderate, informed drinking is most feasible