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While the first GLP-1 was approved by the FDA more than 20 years ago, to treat Type 2 diabetes, the use of these drugs took off in 2021 when Novo Nordisk received approval for a semaglutide drug to treat obesity, with the brand name Wegovy

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Pang L, Lian X, Liu H, Zhang Y, Li Q, Cai Y, et al

B., Wang, R., Marcotte, E

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26,27 Relative weight change at the 12-month time point was also compared using the Wilcoxon rank-sum test in patients who received concurrent ET and those who did not