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Furthermore, the study compared Akkermansia with a dietary intervention, providing important benchmarks of comparison

Early studies suggest Epithalon may restore melatonin rhythmicity and reduce oxidative stress markers, though independent replication at scale is lacking

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Mohammed Taouis, Yacir Benomar Molecular and Cellular Endocrinology.2021

Other amylin-based molecules which are in early stage clinical trials include long-acting amylin agonists and a dual amylin and calcitonin RA (Table 1)