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[PubMed Citation] Astier A, Baud FJ

Neurology of Nutritional Vitamin B12 Deficiency in Infants: Case Series From India and Literature Review. J Child Neurol

Clinical Trials: Impact of B12 Supplementation on Metabolites Below are four graphs showing the response to B12 supplementation of serum B12, holotranscobalamin, MMA, and homocysteine: Eight trials of predominantly older adults with at least mild deficiency (Dangour, 2015

Sure would be great if I had all that

These include blood concentrations of total cobalamin, holo-transcobalamin (vitamin B 12 bound to transcobalamin, one of the two carrier proteins in blood

There are no controlled trials of the combined formulation showing meaningful weight loss, and supplementing patients who are not deficient has not been shown to produce it