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Effective Ways to Avoid a Hangover No evidence supports the claim that B vitamins can prevent a hangover

Any weight loss that follows a shot comes from the lifestyle changes around it, not the injection itself

People with a B12 deficiency might seek out a vitamin B12 injection

However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc

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Conversely, medications like metformin, H2 blockers, and proton pump inhibitors can reduce the absorption of Vitamin B12