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With growing recognition of obesity as a disease in modern society and a sharp rise in its prevalence, pharmacological interventions are now being actively pursued

391 Lactobacillus paracasei R3 and Bacteroides faecis can both restore the integrity of the gut barrier by affecting Th17/Treg homeostasis, which in turn increases the expression of tight junction proteins and regulates the gut microbiota

Combined with adequate protein, resistance training can shift the ratio of fat-to-lean-mass loss from roughly 60/40 to closer to 80/20 or even 85/15

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The most commonly reported side effects are nausea, mild constipation, and reduced appetite, typically most noticeable during the first four to six weeks as the body adjusts to the medication

[DOI] [PubMed] [Google Scholar] 105.Chhabra N., Grill M.F., Singh R.B.H