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all authors revised and edited the manuscript

Patients with dexterity challenges, such as arthritis, neuropathy, or other fine motor skills, may find it hard to apply and remove the patch themselves, requiring extra support

Patients should avoid purchasing unapproved GLP-1 patches marketed online, as these products may be counterfeit or unsafe

Compounded products are not FDA-approved or evaluated by the FDA for safety, quality, and efficacy

Patient Eligibility and Safety Considerations Contrave requires careful patient selection due to bupropion's neuropsychiatric risk profile

In addition to its effects on metabolic regulation, GLP-1, when synthesized within the brain, exhibits neuroprotective properties