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Consistent with the findings in vivo, high glucose increased the proliferation and suppressed apoptosis of PSCs in vitro, whereas GSH prevented these effects (Fig

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Inhibition of tumor growth and metastasis with antisense oligonucleotides (Cantide) targeting hTERT in an in situ human hepatocellular carcinoma model

The gut microbiota-derived deamidated pathway facilitates the utilization of NAM or NR for hepatic NAD + synthesis, suggesting that manipulation of microbiota might offer a new option to manipulate NAD + metabolism