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Pharmaceuticals (Basel, Switzerland), 13(11), 407

Piperlongumine affected various hallmarks of cancer such as cell survival, proliferation, invasion, angiogenesis, epithelial-mesenchymal-transition, and metastases and also inhibited radioresistance and chemoresistance of cancer cells [90,91,92]

doi:10.1139/cjpp-2018-0570

from the UK reported a clinical trial that showed improvement in skin collagen, hydration, elasticity, wrinkles, and scalp and hair parameters following the oral intake of a supplement called Absolute Collagen, containing hydrolyzed collagen (8 g) and vitamin C (60 mg) daily for 12 weeks in men and women (aged 4060 years) [51]

That combination of symptoms is something our team at Southdowns Pharmacy Group hears about regularly