For example, ginseng-derived ginsenoside stimulated GLP-1 secretion in L-cells and decreased hyperglycemia in diabetic models through a sweet taste receptor-mediated signal transduction pathway [202]
While we did not directly manipulate GLP-1 receptors or dopamine signaling in this study, prior work has shown that activation of central GLP-1R can attenuate dopamine release in the nucleus accumbens (Fortin and Roitman, 2017
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However, these synthetic DPP-IV inhibitors have been reported to have a number of adverse effects, such as gastrointestinal adverse reactions, allergic reactions, skin-related side effects, and musculoskeletal disorders
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'+' 292 'GLP-1 RA+' 146