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However, the persistence of interactions differed suggesting subtle distinctions in how the different agonists engage these networks

After propensity score matching, each cohort included 7,561 patients

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For the latter, it is not only known that PAR2 signaling induces IR in adipocytes (125), but PAR2 might also be a substantial contributor to inflammatory and metabolic dysfunction (126)

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"Identification of two transcription activation units in the N-terminal domain of the human androgen receptor"