Common, usually mild: Injection-site reactions (redness, swelling, itching), most frequent with both Mild headache, dizziness, or flushing after injection Initial water retention as IGF-1 rises Transient fatigue in the first 12 weeks Less common, dose-dependent: Carpal tunnel-like wrist symptoms (sign IGF-1 may be too high) Joint discomfort or stiffness Numbness or tingling in extremities Elevated blood glucose (GH antagonizes insulin) The monitoring that matters:IGF-1 (insulin-like growth factor 1, the downstream marker of GH activity) is the lab value that tells you whether youre in a therapeutic range or pushing past it
Recently a meta-analysis examined the possible link between mitochondria and autism, the conclusions of this study are that it is not clear if mitochondrial dysfunction contributes to the development or pathogenesis of ASD or if mitochondrial dysfunction is just an epiphenomenon of ASD[14]
Indeed, genetic and pharmacological replenishment of NAD + improves the age-related biologic function and increases lifespan at least in worms and mice
We will walk you through the protocol, set up monitoring, and get you started
Vasse GF, Melgert BN
Austin: Eakin Press