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Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 939

In clinical trials of GLP-1 medications, adults lost a mean of roughly 15% of body weight over about a year (STEP-1, Novo Nordisk

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Prog Biophys Mol Biol

Hydrate Proactively, Not Reactively GLP-1s can blunt appetite and thirst cues, making it easy to unintentionally under-hydrate

The answer is yes but the more interesting comparison is at the higher end of the response distribution