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The increased population of CD8 + T cells in adipose tissue is hypothesized to promote and maintain the pro-inflammatory M1 phenotype of ATMs with age [94, 102]

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doi: 10.3389/fneur.2025.1663136 Received 10 July 2025 Accepted 18 August 2025 Published 02 September 2025 Volume 16 - 2025 Edited by Elvio Della Giustina, University Hospital of Modena, Italy Reviewed by Shayne Mason, North-West University, South Africa Valentina Magliocca, Bambino Ges Childrens Hospital, IRCCS, Italy Updates Copyright 2025 Tao, Huo, Hao and Liang