Clinical trials demonstrate superior glycemic control and weight reduction compared to selective GLP1 agonists [3] [4]
[PubMed: 1621866] 187
Anecdotal reports from research subjects and biohacking communities describe body composition improvements, increased subjective energy and mental clarity, and minimal side effects, though these uncontrolled observations require cautious interpretation and cannot substitute for rigorous clinical trials
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Fat-soluble vitamins like A and D are harmful in excess, because they build up in fat stores
Additionally, research suggests that semaglutide may also reduce A1C levels in people with or without diabetes, making it a dual-purpose treatment [5]