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Discussion Colistin is a cyclic heptapeptide with an acylated tripeptide side chain that exerts its antimicrobial activity by disrupting the integrity of the bacterial membrane and increasing its permeability, leading to leakage of the cell content, membrane depolarization and cell death 1

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Methylcobalamin is the preferred form for lipotropic protocols because it bypasses the conversion step entirely

Peptides tend to be simpler in structure than proteins, due to their smaller size

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