The shared mechanism is that they imitate glucagon-like peptide-1 (GLP-1) , a hormone the body naturally produces in the intestines and the brainstem after eating
However, Lilly recently (April 21, 2023) registered a new Phase 3b trial (SURMOUNT-5) that will compare Mounjaro against Wegovy in patients with obesity or overweight with weight-related health conditions
"Most GLP-1 medications are peptides, which are large, water-soluble molecules
Anyone thinking about using GLP-1 therapy should talk to reliable healthcare providers, weigh the potential benefits and risks, and stay committed to regular check-ups to keep treatment both effective and safe
Killion EA, Lu SC, Fort M, Yamada Y, Vniant MM, Lloyd DJ
The cost of GLP-1 medications can be high, often ranging from $500 to $1,000 per month