generated HDX-MS and NMR-based model for the tropomyosin-binding domain of the calponin homology-associated smooth muscle (CHASM) protein, where the CHASM intrinsically disordered N-terminal region interacts with the globular C-terminal calponin homology (CH) domain and the cooperativeness between these regions is required for CHASM binding to smooth muscle tropomyosin (MacDonald et al., 2012)
HermanGAStevensCVan DyckKBergmanAYiBDe SmetMet al
The Mistake: Dosing calculation errors
Maintaining adequate selenium status through balanced nutrition remains the most sustainable approach to supporting thyroid function and preventing associated hair problems
Using data from the World Health Organization, they performed a disproportionality analysis, which sought to determine whether there were more reports of suicidal ideation in people taking GLP-1 drugs than would be expected compared to other types of drugs that people with obesity are commonly prescribed, like metformin (13)
At 50mcg per dose, that's 1000 50 = 20 doses