J Affect Disord 268:188200 Trojan E, Chamera K, Bryniarska N, Kotarska K, Lekiewicz M, Regulska M, Basta-Kaim A (2019) Role of chronic administration of antidepressant drugs in the prenatal stress-evoked inflammatory response in the brain of adult offspring rats: involvement of the NLRP3 inflammasome-related pathway
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Neurotensin and alcohol in human studies Two human studies have found links between NTR1 single-nucleotide polymorphism (SNPs) and AUD in humans (Agrawal et al., 2013)
The ensuing neuroinflammation can emerge as long-term cognitive impairment and neurodegeneration (Haruwaka et al., 2019)
Tesamorelin, a synthetic GHRH (growth hormone-releasing hormone) analogue, has been shown to significantly reduce visceral adipose tissue (VAT) 2 in HIV-infected patients with abdominal fat accumulation
Whether DSIP can meaningfully address the underlying dysregulation in narcolepsy is a question the PCAC review will likely examine