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PlexusDx recommends checking in with your medical team if cramping persists despite hydration efforts, as this may signal a need for dose adjustment or additional metabolic support

Geroscience 43 (1), 377394

The MHRA recommends B12 monitoring in patients on long-term metformin treatment, and your GP can arrange appropriate blood tests and prescribe treatment if deficiency is confirmed

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According to the WHO, When it comes to treatment options, psychotherapy and medications are used to help manage the symptoms