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Consequently, we are unable to mechanistically validate the proposed signaling pathways or fully explain the patients unique PFS pattern and potential heterogeneity in treatment response

Starting at a lower dose and titrating gradually allows the GI system to adapt

EMBO Rep 2005

Protect from Light: The refrigerator naturally keeps it dark, but its good practice to store it in its original box or another container to shield it from light whenever the door is opened

The anti-AKT (1:1000, ab227385), anti-phospho-AKT1 (Ser 473) (1:1000, ab81283), anti-FOXO3a (1:1000, ab12162), and anti-phospho-FOXO3a (Ser 253) (1:1000, ab154768) antibodies were purchased from Abcam Corp