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The pineal gland plays a central role in coordinating biological rhythms through the secretion of melatonin and other signaling molecules

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Dosage adjustments or discontinuation may be warranted based on individual tolerance

After reconstitution: Store 28C short-term

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For each article, the following data were extracted by 2 independent reviewers: the quality of the control groups and the homogeneity of the confounding factors between the groups, the level of expression (mRNA, protein) and the direction and amplitude of variation of the candidate biomarker, the adjustments of the results according to the subtypes of endometriosis, the phase of the menstrual cycle, the treatments and the symptoms and the ROC curve analysis to highlight diagnostic accuracy if available