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The reduction in right ventricular end-diastolic area (RVEDA) and the improvements in right ventricular fractional area change (RVFAC) and tricuspid annular plane systolic excursion (TAPSE) suggest that semaglutide not only attenuates RV dilation but also enhances the contractile function of the RV

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10.3892/ijmm.2018.3509 52 McIntyreN.HoldsworthC

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Strategic manufacturing shifts: Entry into peptide therapeutics: Domestic firms are scaling capabilities in high-value biologics Device-linked delivery: Growth in injector pens and cold-chain logistics is creating adjacent opportunities Cost arbitrage: Indias manufacturing efficiency supports competitive global pricing Localization strategies: Eli Lilly has already invested in manufacturing infrastructure in Hyderabad to de-risk supply chains This transition aligns with Indias long-term ambition to move up the pharmaceutical value chainfrom volume-driven generics to innovation-led manufacturing

doi: 10.1016/j.ejphar.2018.01.037 54 MatthysPHatseSVermeireKWuytsABridgerGHensonGWet al