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The potential of TB-500 on angiogenesis and migration was assessed using MTT assays for cell viability, tube formation assays for angiogenesis, and wound healing assays for the migratory ability of HUVEC

Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine

31 Megaesophagus resolved with medical treatment and surgical correction of the diaphragmatic defect

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Coverage includes FDA-approved medications and follow-up care