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It relies on a protein called intrinsic factor in your stomach to be absorbed

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Pregnancy and Breastfeeding Not recommended while pregnant or nursing

Lack of either FOLIC ACID or VITAMIN B12 can create anaemias

Initial treatments may require several injections per week, followed by maintenance doses every month

Stacking & Combinations Because its mechanism is NAD+ preservation, the logical research pairing is with the NAD+ pathway : in some research framings, an NNMT inhibitor like 5-Amino-1MQ is discussed alongside NAD+ precursors, on the reasoning that inhibiting the enzyme that drains NAD+ and supplying more NAD+ substrate address the same bottleneck from two directions