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Additionally, the FOXO4-p53 interaction contributes to the maintenance of senescent cells by activating the transcription of their common target gene, p21cip1, which suppresses apoptosis 36

Raz, Y., Cohen, N., Shani, O., Bell, R

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Having a B12 deficiency for a long period of time can make you more at risk for health conditions such as dementia and infertility, so it is important to make sure that your levels are properly balanced

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In addition to disruption of circadian rhythms by repeated phase shifts (jet lag), foundational science research has examined the role of circadian disruption by light at night in stroke outcome