Its like walking in the dark
Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]
Tirzepatide is an approved, extensively studied dual agonist with a proven safety record, commercial availability, and the most comprehensive Phase 3 dataset in the GLP-1 class
Sun damage, smoking, and hydration also play a role
Some providers may choose a lowerthanstandard therapeutic dose
Phase 2 trial data shows average weight loss of 24.2% at 48 weeks on the 12 mg dose, which translates to roughly 58 pounds for the average participant