Choosing a Shot Day: Pick a day where you have a lighter schedule for the following 24 hours
In addition to the hormones GIP and glucagon, other hormones such as estrogen, peptide tyrosine tyrosine (PYY), gastrin, xenin, and fibroblast growth factor 21 can be good candidates to pair with GLP-1 and create dual agonists that have anti-diabetic and anti-obesity effects
What the research shows: In the landmark STEP clinical trials, patients taking semaglutide lost an average of 15% of their body weight over 68 weeks
Transdermal absorption of large molecules is governed by skin barrier physics, not sex hormones, and the barrier constraint applies identically
What really scared me was telling my audience
GLP-1 agonists (glucagon-like peptide-1 receptor agonists) work by mimicking a hormone your body naturally produces to manage blood sugar and digestion