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Naltrexone: This active ingredient is an opioid receptor antagonist and can influence signaling pathways associated with reward and craving

Consult with your healthcare provider to determine if a combination therapy is appropriate for you

No data exist on the safety and efficacy of valerian in nursing mothers or infants

Injection: Use in children: There is no information on the use of this drug in children

doi: 10.3389/fevo.2023.1194611 Received 27 March 2023 Accepted 31 May 2023 Published 28 June 2023 Volume 11 - 2023 Edited by Pavel Stopka, Charles University, Czechia Reviewed by Mousumi Poddar Sarkar, University of Calcutta, India

It also raises the risk of not getting enough important nutrients