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Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

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doi: 10.1111/cns.14060 210 SchumacherHRJr.BoiceJADaikhDIMukhopadhyaySMalmstromKNgJet al

Cardiovascular Outcomes This section reviews current evidence regarding GLP-1 RAs effects on MACE, PAD, CAD, HF, blood pressure, and AF, with detailed findings of trials and meta-analyses discussed in Tables 1 and 2 Major Adverse Cardiac Events Among Patients with T2DM Strong evidence supports using GLP-1 RAs to reduce MACE among patients with T2DM and established CVD