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In this review we will focus on (a) GSH depletion as a fundamental risk factor for diseases like chronic obstructive pulmonary disease and atherosclerosis (ischemic heart disease and stroke), (b) importance of oxidative stress and antioxidants in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19 disease, (c) significance of GSH to counteract persistent damaging inflammation, inflammaging and early (premature) inflammaging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses in younger individuals, and (d) new therapies that include antioxidant defenses restoration

This broad anti-inflammatory effect protects multiple retinal cell types simultaneously

[1] Specifically, the tripeptide sequence Gly-His-Lys may naturally signal the presence of broken collagen

(trusted non-journal) References References An J, et al

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Vitamin C contributes to the normal function of the nervous system