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Proteolytic clearance (no CYP450), no major pharmacokinetic interactions expected
Retatrutide is a triple receptor agonist targeting GLP-1, GIP, and glucagon pathways
Moreover, the various steps by which GLP-1 can act to limit inflammation still remain unresolved
But if were really talking about treating obesity, those microdosing doses are not going to be effective for most people, and so I worry people are going to pay for it cause its cheaper and then its not going to work for them and theyre going to think heres one more thing thats not working for me. In Diet, Drugs, and Dopamine, former FDA Commissioner David A
The study was encouraging, but it was relatively small and involved a defined population