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Niacin, a closely related form of vitamin B3, is known to transiently impair insulin sensitivity and raise blood glucose levels

Some nutrients, dietary supplements, and naturally occurring substances found in nutraceuticals (62, 63) may help fight some diseases by reducing oxidative stress

By Donna Monthei, RDN, LD | Originally Published: July 10, 202 5 | Medically Reviewed on June 19, 2026 If youre taking Ozempic (semaglutide), Wegovy (semaglutide), Mounjaro (tirzepatide), or Zepbound (tirzepatide) for weight loss or diabetes management, congratulationsyouve joined millions of people experiencing remarkable metabolic improvements

The more we know, the better we can help you

The maintenance dose usually sits at 2.4 mg for adults, but if you find this difficult to tolerate, your provider may suggest reducing it to 1.7 mg

Then, get ready for your first dose your first dose in less than a week if paying cash, and two weeks if using insurance