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Individuals with risk factors for B12 deficiency including strict vegans, those with gastrointestinal conditions, patients taking long-term metformin or proton pump inhibitors, and older adultsshould discuss screening with their GP, even in the absence of obvious symptoms

9 In some cases, symptoms associated with elevated vitamin B12 levels may actually occur in people undergoing treatment for a vitamin B12 deficiency rather than from excessive intake itself

The process typically takes only a few minutes

Though more invasive, BMAC is another promising frontier in regenerative treatments

Run once daily with gradual titration across the cycle

Many researchers prefer adding 2ml to a 5mg vial (giving 2,500mcg/ml) as this reduces concentration to a range where syringe measurements are more precise