The medication will help you lose weight, but avoiding nasty side effects like muscle loss and severe constipation takes work
Numerous studies have found that GLP-1 agonists can be effective for weight loss, blood sugar management, and heart health, especially when combined with diet and lifestyle changes
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Exendin-4 significantly increased insulin level and phosphorylation of insulin receptor substrate 1 (IRS-1) in rat hippocampus, and could not change the status of tau phosphorylation without insulin in HT22 neurons, suggesting that insulin is required in reduction of tau hyperphosphorylation by GLP-1R agonists (154)
Lifestyle changes might help improve high blood pressure, but many people need to be on medication for it for the rest of their lives and its very similar in weight management, she notes
Beyond weight and blood sugar, studies like the SELECT trial have shown that GLP-1s also reduce the risk of heart attacks and strokes