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Morning stiffness eases

Diabetes is the leading cause of new blindness in adults, end-stage renal disease, and non-traumatic lower limb amputation making precise clinical documentation and coding directly impactful on care management and risk adjustment

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Furthermore, inefficient autophagy/mitophagy of damaged biomolecules and organelles leads to a vicious cycle in the cells, which ultimately exacerbates the progression of the CIPN typical neurodegeneration

Although both EPA and DHA belong to the n-3 PUFA family, they demonstrate divergent mechanistic profiles: DHA consistently suppresses TGF-/SMAD signaling and inflammasome activation, whereas EPA exhibits variable effects and may exacerbate steatosis under conditions of impaired mitochondrial -oxidation