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Helical peptides that are known to play key roles in maintaining metabolic homeostasis include, among others, glucagon (GCG) and glucagon-like peptide-1 (GLP-1), which signal and agonise the G-protein-coupled receptors (GPCR) GCGR and GLP-1R, respectively 1

These results are also in agreement with earlier reports 44, 52

PHGDH acts as a central regulator, and its inhibitors can disrupt redox balance, offering promising therapeutic targets for tumor intervention

Frohnert BI, Sinaiko AR, Serrot FJ, Foncea RE, Moran A, Ikramuddin S, et al

Neonatal vitamin A supplementation and vitamin a status are associated with gut microbiome composition in Bangladeshi infants in early infancy and at 2 years of age