The take-away : Having optimal levels of B6 may help protect us from the effects of stress, including depressive symptoms
It has been shown that prolactin receptor deficient mice have reduced beta cell mass and lower insulin content, implying that prolactin plays a key role in developing beta cells during embryogenesis and gestation (73, 74)
Insurance-covered GLP-1 medications: If your insurance covers brand-name Wegovy or Mounjaro, platforms like Found or Ro that work with insurance will be dramatically cheaper than Marek's cash-pay compounded GLP-1 options
Within 2-4 weeks of daily supplementation you should have elevated levels of plasma L-Carnitine as well as fully saturated creatine stores
Of note, since publication of the 2025 American Diabetes Association Standards of Care, a new trial with oral semaglutide has demonstrated positive outcomes in reducing major adverse cardiac events in patients with diabetes at high risk of CV events (existing ASCVD and/or CKD)
P Natl Acad Sci USA 93:37043709 [DOI] [PMC free article] [PubMed] [Google Scholar] Li K, Reichmann H (2016) Role of iron in neurodegenerative diseases