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17,18 Additionally, other gut microorganisms, including Deferribacteraceae, Anaeroplasmataceae, Prevotellaceae, and Enterobacteriaceae, also participate in this process

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No direct adverse effects on male fertility was observed at doses up to 1 mg/kg/day, a high dose yielding an estimated systemic exposure 11-times the exposure in obese humans at the MRHD, based on plasma AUC comparison