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Specifically, KLF2 activates thrombomodulin, reduces plasminogen activator inhibitor (PAI)-1 expression and inhibits the cytokine-driven TF expression, ultimately preventing or prolonging clotting time under basal or inflammatory conditions [81,82,83] (Fig

doi: 10.1016/j.jpeds.2011.03.049 39 PalladinoAASayedSLevitt KatzLEGallagherPRDe LeonDD

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