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Pretreatment with L-NNA (20 mg/kg i.p.) prior to PTX (10 mg/kg i.p.) produced a small but significant decrease in SOD activity, as compared to PTX-alone and addition of L-arginine (50 mg/kg i.g.) to L-NNA (20 mg/kg i.p.), prior to intraperitoneal PTX application, resulted in the increment of SOD activity similar to that observed in the PTX-treated rats without L-NNA pretreatment ( Fig

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doi: 10.1007/s00134-023-07263-w [PubMed] 38170117 Gidal BE, Resnick T, Smith MC, Wheless JW