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Insulin Resistance and Metabolic Signaling A subset of women with endometriosis experience insulin resistance or metabolic dysfunction, often overlapping with PCOS or chronic inflammation

The 10 mg dose of tirzepatide showed greater weight reduction versus semaglutide 1 mg by -1.8 mmHg (-3.4 to -0.1) while the 15 mg dose of tirzepatide reduced an additional -3 mmHg (-4.6 to -1.3) compared to semaglutide [65]

& Raybould, H

It binds to GHRH receptors on your pituitary and prompts a pulse of GH

Semaglutide is meant to be titrated up gradually, with most individuals finding the 0.50mg-1.00mg dose to be the "sweet spot" for weight loss