The research project was approved by our institution (Universidad Complutense de Madrid) and by the "Real Federacin Hpica Espaola"
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Future pharmaceutical CagriSema Anticipated FDA approval: Phase 3 trials completed FDA submission expected 2024-2025 Approval likely 2025-2026 Brand name: CagriSema Pharmaceutical pricing (projected): Likely $1,200-1,500/month without insurance Similar to Wegovy/Zepbound pricing Insurance coverage uncertain initially Patient assistance programs may be available Insurance considerations: May cover if BMI 30 with comorbidity Or BMI 27 with diabetes/hypertension Prior authorization required Step therapy (try semaglutide first) When pharmaceutical available: Easier administration (pre-filled pen likely) Medical support included Quality guaranteed Prescription required May or may not be cheaper than research peptides Troubleshooting CagriSema dosing issues Common problems and solutions
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doi:10.1016/j.tree.2022.04.006
Journal of Biological Chemistry 277, 44765-44771CrossRefGoogle ScholarPubMed 77Shih, A.Y., Erb, H., Sun, X