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Chemical and structural modifications of RNAi therapeutics

doi: 10.1038/s41575-020-0344-2 153 da SilvaTFCasarottiSNde OliveiraGLVPennaALB

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2019;14: e0212019

However, the potentially large target patient population, as well as the increased utilization and high drug costs, are a growing concern for many plan sponsors