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5,6 Timely intervention with diet and lifestyle changes and nutritional support can slow or reverse fat accumulation and liver damage, even in some cases with evident inflammation and fibrosis (scarring)

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The elevated blood cell mass results in hyperviscosity, which may manifest with fatigue, facial flushing, pruritus, erythromelalgia, headaches, dizziness, and, in severe cases, thromboembolic events (e.g., stroke, Budd-Chiari syndrome)